What is the largest tribal grouping of Native Americans in the United States?            
            
                                                                                   
            Cherokee. According to the 2000 census, 281,069 U.S. citizens self-identify as Cherokee. These numbers are closely followed by  	Navajo (269,202). Other tribal groups are considerably smaller, only Sioux (108,272) and Chippewa (105,907) exceed 100,000.